Qivana of Honolulu Products Line: Prime, Qore and Metaboliq
Nitric Oxide and the Immune Response
Institute of Clinical Microbiology, Immunology and Hygiene, Friedrich-Alexander-University of Erlangen-Nuremberg, Wasserturmstrasse 3-5, D-91054 Erlangen, Germany. firstname.lastname@example.org
Nitric Oxide has been recognized as one of the most versatile players in the immune system
During the past two decades, nitric oxide (NO) has been recognized as one of the most versatile players in the immune system. It is involved in the pathogenesis and control of infectious diseases, tumors, autoimmune processes and chronic degenerative diseases. Because of its variety of reaction partners (DNA, proteins, low-molecular weight thiols, prosthetic groups, reactive oxygen intermediates), its widespread production (by three different NO synthases (NOS) and the fact that its activity is strongly influenced by its concentration, NO continues to surprise and perplex immunologists.
Today, there is no simple, uniform picture of the function of NO in the immune system. Protective and toxic effects of NO are frequently seen in parallel. Its striking inter- and intracellular signaling capacity makes it extremely difficult to predict the effect of NOS inhibitors and NO donors, which still hampers therapeutic applications.
1 Species differences in macrophage NO production are important. [Nat Immunol. 2002]
PMID: 11577346 [PubMed - indexed for MEDLINE]
Nat Immunol. 2001 Oct;2(10):907-16.
Publication Types, MeSH Terms, Substances
LinkOut - more resources
Buy All of Your Qivana Products Here, We Ship Worldwide!
Nitric Oxide, Aging and Antiaging
Nitric Oxide in Athletic Performance
Nitric Oxide Benefits & Roles
Nitric Oxide & the Brain
Nitric Oxide & the Cardiovascular System
Nitric Oxide (NO) and Diabetes
Nitric Oxide Foods & Herbs That Increase It
Nitric Oxide & Nanomedicine
Nitric Oxide, Sex, Libido, and Erectile Dysfunction (ED)